Accession
MI0000366
Description
Drosophila melanogaster
dme-mir-281-1 precursor miRNA mir-46
Gene
family?
family?
RF00249;
mir-46
Literature search
13 open access papers mention dme-mir-281-1
(31 sentences)
(31 sentences)
Sequence
252519
reads,
2379
reads per million, 49 experiments
cgaauaagugaauAAAGAGAGCUGUCCGUCGACAGUccagaaacuauuuaauaucacUGUCAUGGAAUUGCUCUCUUUGUauaauauucg
((((((.....(((((((((((..(((((.((((((...................)))))))))))...)))))))))))....))))))
((((((.....(((((((((((..(((((.((((((...................)))))))))))...)))))))))))....))))))
Structure
aguga -UG C ccagaaac
cgaaua auAAAGAGAGC UCCGU GACAGU u
|||||| ||||||||||| ||||| |||||| a
gcuuau UGUUUCUCUCG AGGUA CUGUca u
-aaua UUA - cuauaauu
Annotation confidence
High
Do you think this miRNA is real?
Comments
miR-281 was reported independently in references [1] and [2]. The sequence in this entry is from reference [2] which identified a 23 nt excised sequence from the 3' arm of the precursor by cloning. Reference [1] reported the reverse complement of this foldback precursor from computational prediction and northern blotting. The predicted mature sequence (5' and 3' ends unknown) from the 3' arm of the reverse complement was named miR-281a in reference [1] and is designated miR-281-1* here.
Genome context
chr2R: 12170373-12170462 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from dme-mir-281-1
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Database links
Mature dme-miR-281-1-5p
| Accession | MIMAT0000344 |
| Description | Drosophila melanogaster dme-miR-281-1-5p mature miRNA |
| Sequence | 14 - AAAGAGAGCUGUCCGUCGACAGU - 36 |
| Evidence |
experimental
Northern [1], 454 [3-4], Illumina [4] |
| Database links |
|
Mature dme-miR-281-3p
| Accession | MIMAT0000345 |
| Description | Drosophila melanogaster dme-miR-281-3p mature miRNA |
| Sequence | 58 - UGUCAUGGAAUUGCUCUCUUUGU - 80 |
| Evidence |
experimental
Northern [1], cloned [2], 454 [3-4], Illumina [4] |
| Database links |
|
References
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