Stem-loop mmu-mir-539

Accession

MI0003520

Symbol

MGI: Mir539

Description

Mus musculus mmu-mir-539 precursor miRNA

Literature search

11 open access papers mention mmu-mir-539
(18 sentences)

Sequence

2628 reads, 50 reads per million, 49 experiments

uacuugaGGAGAAAUUAUCCUUGGUGUGUuggcucuuuuggaugaauCAUACAAGGAUAAUUUCUUUUUgagua
(((((((((((((((((((((((.((((((.(.(((...)))).)).)))))))))))))))))))))))))))

Structure

                       G    -  g c   u 
uacuugaGGAGAAAUUAUCCUUG UGUG Uu g ucu  
||||||||||||||||||||||| |||| || | ||| u
augagUUUUUCUUUAAUAGGAAC AUAC aa u agg  
                       -    u  g -   u 

Annotation confidence Medium

Genome context

chr12: 109728129-109728202 [+]

Clustered miRNAs

15 other miRNAs are < 10 kb from mmu-mir-539

Mature mmu-miR-539-5p

• Accession: MIMAT0003169
• Description: Mus musculus mmu-miR-539-5p mature miRNA
• Sequence: 8 - GGAGAAAUUAUCCUUGGUGUGU - 29
• Evidence: experimental ; MPSS [2], miRAP-cloned [3], Illumina [4-5]

Mature mmu-miR-539-3p

• Accession: MIMAT0017208
• Description: Mus musculus mmu-miR-539-3p mature miRNA
• Sequence: 48 - CAUACAAGGAUAAUUUCUUUUU - 69
• Evidence: experimental ; Illumina [5]

References

1. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


2. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


3. PubMed ID: 16582102
   The expression profile of microRNAs in mouse embryos
   "Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K, Mirochnitchenko O, Inouye M, Kato I"
   "Nucleic Acids Res (2006) 34:1765-1771


4. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267


5. PubMed ID: 16973894
   Mouse microRNA profiles determined with a new and sensitive cloning method
   "Takada S, Berezikov E, Yamashita Y, Lagos-Quintana M, Kloosterman WP, Enomoto M, Hatanaka H, Fujiwara S, Watanabe H, Soda M, Choi YL, Plasterk RH, Cuppen E, Mano H"
   "Nucleic Acids Res (2006) 34:e115