Stem-loop bta-mir-30b

Accession

MI0004761

Description

Bos taurus bta-mir-30b precursor miRNA

Literature search

94 open access papers mention bta-mir-30b
(449 sentences)

Sequence

4431996 reads, 1885.0 reads per million, 321 experiments

ccaaguuuucaguucaUGUAAACAUCCUACACUCAGCUguaacacacgagucggCUGGGAGGUGGAUGUUUACUUCagcugacuugga
(((((...((((((...((((((((((.((.((((((((..((......))))))))))..))))))))))))...))))))))))).

Structure

-     uuu      caU          U  -A        ua  ac 
 ccaag   ucaguu   GUAAACAUCC AC  CUCAGCUg  ac  a
 |||||   ||||||   |||||||||| ||  ||||||||  ||   
 gguuc   agucga   CAUUUGUAGG UG  GGGUCggc  ug  c
a     ---      CUU          -  GA        --  ag 

Annotation confidence High

Comments

High-throughput sequencing suggests that the dominant miRNA arises from the 3' arm of this precursor [2], in contrast to earlier cloning studies.

Genome context

14: 7045567-7045654 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from bta-mir-30b

Mature bta-miR-30b-5p

• Accession: MIMAT0003547
• Description: Bos taurus bta-miR-30b-5p mature miRNA
• Sequence: 17 - UGUAAACAUCCUACACUCAGCU - 38
• Evidence: experimental ; cloned [1-2], Illumina [3]

Mature bta-miR-30b-3p

• Accession: MIMAT0012534
• Description: Bos taurus bta-miR-30b-3p mature miRNA
• Sequence: 55 - CUGGGAGGUGGAUGUUUACUUC - 76
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17105755
   Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues
   "Coutinho LL, Matukumalli LK, Sonstegard TS, Van Tassell CP, Gasbarre LC, Capuco AV, Smith TP"
   "Physiol Genomics (2007) 29:35-43


2. PubMed ID: 17306260
   Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland
   "Gu Z, Eleswarapu S, Jiang H"
   "FEBS Lett (2007) 581:981-988


3. PubMed ID: 19633723
   Repertoire of bovine miRNA and miRNA-like small regulatory RNAs expressed upon viral infection
   Glazov EA, Kongsuwan K, Assavalapsakul W, Horwood PF, Mitter N, Mahony TJ
   PLoS One (2009) 4:e6349