Stem-loop bta-mir-345

Accession

MI0005019

Description

Bos taurus bta-mir-345 precursor miRNA mir-345

Gene
family

RF01044; mir-345

Literature search

4 open access papers mention bta-mir-345
(7 sentences)

Sequence

3415 reads, 139 reads per million, 73 experiments

acccaaacccaggucuGCUGACUCCUAGUCCAGUGCUugugauggcuggugggcCCUGAACUAGGGGUCUGGAGgccuggguuugaauauc
...(((((((((((((.(.((((((((((.(((.((((((........)))))).))).)))))))))).).)))))))))))))......

Structure

---acc             G U          C   U      gau 
      caaacccaggucu C GACUCCUAGU CAG GCUugu   g
      ||||||||||||| | |||||||||| ||| ||||||    
      guuuggguccgGA G CUGGGGAUCA GUC cgggug   g
cuauaa             G U          A   C      guc 

Annotation confidence High

Comments

High-throughput sequencing suggests that the dominant miRNA arises from the 3' arm of this precursor [2], in contrast to earlier cloning studies.

Genome context

chr21: 67146236-67146326 [+]

Mature bta-miR-345-5p

• Accession: MIMAT0003800
• Description: Bos taurus bta-miR-345-5p mature miRNA
• Sequence: 17 - GCUGACUCCUAGUCCAGUGCU - 37
• Evidence: experimental ; cloned [1], Illumina [2]

Mature bta-miR-345-3p

• Accession: MIMAT0012535
• Description: Bos taurus bta-miR-345-3p mature miRNA
• Sequence: 55 - CCUGAACUAGGGGUCUGGAG - 74
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 17105755
   Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues
   "Coutinho LL, Matukumalli LK, Sonstegard TS, Van Tassell CP, Gasbarre LC, Capuco AV, Smith TP"
   "Physiol Genomics (2007) 29:35-43


2. PubMed ID: 19633723
   Repertoire of bovine miRNA and miRNA-like small regulatory RNAs expressed upon viral infection
   Glazov EA, Kongsuwan K, Assavalapsakul W, Horwood PF, Mitter N, Mahony TJ
   PLoS One (2009) 4:e6349