Stem-loop sme-let-7a

Accession

MI0005122

Description

Schmidtea mediterranea sme-let-7a precursor miRNA

Literature search

2 open access papers mention sme-let-7a
(9 sentences)

Sequence

aucaaauucaUGAGGUAGAAUGUUGGAUGACUaagguaaagguaacauaucagaGCUGUUCAAUUUUCUGCCUUUAAaauuugau
((((((((...(((((((((.((((((((.((..((((.........))))..)).)))))))).)))))))))...))))))))

Structure

        caU         U        A  aa    aag 
aucaaauu   GAGGUAGAA GUUGGAUG CU  ggua   g
||||||||   ||||||||| |||||||| ||  ||||   u
uaguuuaa   UUCCGUCUU UAACUUGU Ga  cuau   a
        AAU         U        C  ga    aca 

Annotation confidence Not enough data

Genome context

Unknown

Mature sme-let-7a-5p

• Accession: MIMAT0003952
• Description: Schmidtea mediterranea sme-let-7a-5p mature miRNA
• Sequence: 11 - UGAGGUAGAAUGUUGGAUGACU - 32
• Evidence: experimental ; cloned [1], Northern [1], 454 [2], Illumina [2]

Mature sme-let-7a-3p

• Accession: MIMAT0012087
• Description: Schmidtea mediterranea sme-let-7a-3p mature miRNA
• Sequence: 55 - GCUGUUCAAUUUUCUGCCUUUAA - 77
• Evidence: experimental ; 454 [2], Illumina [2-3]

References

1. PubMed ID: 16849698
   MicroRNAs from the Planarian Schmidtea mediterranea: a model system for stem cell biology
   "Palakodeti D, Smielewska M, Graveley BR"
   "RNA (2006) 12:1640-1649


2. PubMed ID: 19564616
   High-resolution profiling and discovery of planarian small RNAs
   "Friedlander MR, Adamidi C, Han T, Lebedeva S, Isenbarger TA, Hirst M, Marra M, Nusbaum C, Lee WL, Jenkin JC, Sanchez Alvarado A, Kim JK, Rajewsky N"
   "Proc Natl Acad Sci U S A (2009) 106:11546-11551


3. PubMed ID: 19553344
   Deep sequencing identifies new and regulated microRNAs in Schmidtea mediterranea
   "Lu YC, Smielewska M, Palakodeti D, Lovci MT, Aigner S, Yeo GW, Graveley BR"
   "RNA (2009) 15:1483-1491