Stem-loop sme-mir-2a-1

Accession

MI0005131

Description

Schmidtea mediterranea sme-mir-2a-1 precursor miRNA

Gene family

MIPF0000049; mir-2

Sequence

guucauuuaugugAGUUCCAGUGUGCUAUGAUGUAuauuucuaaaaauuucuauaUAUCACAGCCCCGCUUGGAACGCUaauuaaugaau
(((((((.((..(.(((((((((.(((.(((((((((..............))))))))).)))..))).)))))).)..)).)))))))

Structure

       u  gu A      -   -U   A         uuucua 
guucauu au  g GUUCCA GUG  GCU UGAUGUAua      a
||||||| ||  | |||||| |||  ||| |||||||||       
uaaguaa ua  C CAAGGU CGC  CGA ACUAUauau      a
       u  aU G      U   CC   C         cuuuaa 

Annotation confidence Not enough data

Genome context

Contig1403: 125998-126087 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from sme-mir-2a-1

Mature sme-miR-2a-1-5p

• Accession: MIMAT0003964
• Description: Schmidtea mediterranea sme-miR-2a-1-5p mature miRNA
• Sequence: 14 - AGUUCCAGUGUGCUAUGAUGUA - 35
• Evidence: experimental ; 454 [2], Illumina [2-3]

Mature sme-miR-2a-3p

• Accession: MIMAT0003963
• Description: Schmidtea mediterranea sme-miR-2a-3p mature miRNA
• Sequence: 56 - UAUCACAGCCCCGCUUGGAACGCU - 79
• Evidence: experimental ; cloned [1], Northern [1], 454 [2], Illumina [2]

References

1. PubMed ID: 16849698
   MicroRNAs from the Planarian Schmidtea mediterranea: a model system for stem cell biology
   "Palakodeti D, Smielewska M, Graveley BR"
   "RNA (2006) 12:1640-1649


2. PubMed ID: 19564616
   High-resolution profiling and discovery of planarian small RNAs
   "Friedlander MR, Adamidi C, Han T, Lebedeva S, Isenbarger TA, Hirst M, Marra M, Nusbaum C, Lee WL, Jenkin JC, Sanchez Alvarado A, Kim JK, Rajewsky N"
   "Proc Natl Acad Sci U S A (2009) 106:11546-11551


3. PubMed ID: 19553344
   Deep sequencing identifies new and regulated microRNAs in Schmidtea mediterranea
   "Lu YC, Smielewska M, Palakodeti D, Lovci MT, Aigner S, Yeo GW, Graveley BR"
   "RNA (2009) 15:1483-1491