Stem-loop sme-mir-2d

Accession

MI0005135

Description

Schmidtea mediterranea sme-mir-2d precursor miRNA

Sequence

gugacauuuugccucuuacgGACAUCAUUAUUUGACUGUCGAUagauauugguaacauuauuuugguaguaUCACAGCCAAAUUUGAUGUCCuaaauaagguagucac
(((((....(((((.(((.((((((((..(((((.((((.....(((((((.(((.......))).))))))))))).))))).)))))))))))...))))))))))

Structure

     auuu     --c   c        UU     A    CGAUa       g   ca 
gugac    ugccu   uua gGACAUCA  AUUUG CUGU     gauauug uaa  u
|||||    |||||   ||| ||||||||  ||||| ||||     ||||||| |||  u
cacug    augga   aau CCUGUAGU  UAAAC GACA     CUaugau guu  a
     ----     aua   -        -U     C    -----       g   uu 

Annotation confidence Low

Genome context

Contig1374: 32443-32550 [-]

Clustered miRNAs

3 other miRNAs are < 10 kb from sme-mir-2d

Mature sme-miR-2d-5p

• Accession: MIMAT0012095
• Description: Schmidtea mediterranea sme-miR-2d-5p mature miRNA
• Sequence: 21 - GACAUCAUUAUUUGACUGUCGAU - 43
• Evidence: experimental ; Illumina [2-3]

Mature sme-miR-2d-3p

• Accession: MIMAT0003968
• Description: Schmidtea mediterranea sme-miR-2d-3p mature miRNA
• Sequence: 72 - UCACAGCCAAAUUUGAUGUCC - 92
• Evidence: experimental ; cloned [1], Northern [1], 454 [2], Illumina [2]

References

1. PubMed ID: 16849698
   MicroRNAs from the Planarian Schmidtea mediterranea: a model system for stem cell biology
   "Palakodeti D, Smielewska M, Graveley BR"
   "RNA (2006) 12:1640-1649


2. PubMed ID: 19564616
   High-resolution profiling and discovery of planarian small RNAs
   "Friedlander MR, Adamidi C, Han T, Lebedeva S, Isenbarger TA, Hirst M, Marra M, Nusbaum C, Lee WL, Jenkin JC, Sanchez Alvarado A, Kim JK, Rajewsky N"
   "Proc Natl Acad Sci U S A (2009) 106:11546-11551


3. PubMed ID: 19553344
   Deep sequencing identifies new and regulated microRNAs in Schmidtea mediterranea
   "Lu YC, Smielewska M, Palakodeti D, Lovci MT, Aigner S, Yeo GW, Graveley BR"
   "RNA (2009) 15:1483-1491