Stem-loop cre-MIR919

Accession

MI0005709

Description

Chlamydomonas reinhardtii cre-MIR919 precursor miRNA

Sequence

aaugcgggacgucugcgccgcacaugUCUCAGGAGGACAUCGCCACUauuagcaagcuacuucaggguaucucggucagcauuucguuuggcaagauguccgcuucagguacacgccgcucacgcgaugaaggcgucaucgcaugagcggcgcguacccggaguggacgucuugccAAUCGAGAUGCUGACCGAGAUacccuccagcagcuugcuacuacggacgaucucuuccugagacaugugcggugcagacgucucguauu
(((((((((((((((((((((((((((((((((((((.((((((..((.(((((((((.((..(((((((((((((((((((((((.(((((((((((((((((((.(((((.(((((((((.(((((((.....))))))).))))))))).))))).))))))))))))))))))).)))))))))))))))))))))))..)).))))))))).)).)).)))).)))))))))))))))))))))))))))))))))))))

Structure

                                     C    -  AC  u         a  uc                       u                   a     a         c       a 
aaugcgggacgucugcgccgcacaugUCUCAGGAGGA AUCG CC  Ua uagcaagcu cu  aggguaucucggucagcauuucg uuggcaagauguccgcuuc gguac cgccgcuca gcgauga g
||||||||||||||||||||||||||||||||||||| |||| ||  || ||||||||| ||  ||||||||||||||||||||||| ||||||||||||||||||| ||||| ||||||||| ||||||| g
uuaugcucugcagacguggcguguacagaguccuucu uagc gg  au aucguucga ga  ucccaUAGAGCCAGUCGUAGAGC AAccguucugcaggugagg ccaug gcggcgagu cgcuacu c
                                     c    a  -c  c         c  cc                       U                   c     c         a       g 

Annotation confidence Not enough data

Comments

Zhao et al. and Molner et al. independently identified a number of miR/miR* pairs expressed from this hairpin precursor [1,2]. The predominant product by extensive cloning is named here miR919.1 [2]. The second product (miR919.2) is also shown, but others are omitted for clarity.

Genome context

scaffold_6: 1014120-1014384 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from cre-MIR919

Mature cre-miR919.2

• Accession: MIMAT0004399
• Description: Chlamydomonas reinhardtii cre-miR919.2 mature miRNA
• Sequence: 27 - UCUCAGGAGGACAUCGCCACU - 47
• Evidence: experimental ; cloned [1-2]

Mature cre-miR919.1

• Accession: MIMAT0004969
• Description: Chlamydomonas reinhardtii cre-miR919.1 mature miRNA
• Sequence: 177 - AAUCGAGAUGCUGACCGAGAU - 197
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17470535
   A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii
   "Zhao T, Li G, Mi S, Li S, Hannon GJ, Wang XJ, Qi Y"
   "Genes Dev (2007) 21:1190-1203


2. PubMed ID: 17538623
   miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii
   "Molnar A, Schwach F, Studholme DJ, Thuenemann EC, Baulcombe DC"
   "Nature (2007) 447:1126-1129