Stem-loop cin-let-7a-1

Accession

MI0007149

Description

Ciona intestinalis cin-let-7a-1 precursor miRNA

Literature search

4 open access papers mention cin-let-7a-1
(22 sentences)

Sequence

88202 reads, 12813.0 reads per million, 9 experiments

auggccgugaccacaAUGAGGUAGUAGGUUAUGCAGUuauagccucccuuuuauacugaguggagcacaggagauacUGUGUAACCUUCUGCCUUUGUggcuucguguuu
..(((((...(((((..(((((((.((((((((((((.((..((((((((.......))).))).....))..)))))))))))))).))))))))))))...)).))).

Structure

au   -  uga     AU       U            u  ag  -----   -   uu 
  ggc cg   ccaca  GAGGUAG AGGUUAUGCAGU au  cc     ucc cuu  a
  ||| ||   |||||  ||||||| |||||||||||| ||  ||     ||| |||  u
  uug gc   ggUGU  UUCCGUC UCCAAUGUGUca ua  gg     agg gag  a
-u   u  uuc     --       U            -  ga  acacg   u   uc 

Annotation confidence High

Genome context

ref|NC_020169.1|: 2157406-2157515 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from cin-let-7a-1

Mature cin-let-7a-5p

• Accession: MIMAT0006086
• Description: Ciona intestinalis cin-let-7a-5p mature miRNA
• Sequence: 16 - AUGAGGUAGUAGGUUAUGCAGU - 37
• Evidence: experimental ; Illumina [2]

Mature cin-let-7a-1-3p

• Accession: MIMAT0015247
• Description: Ciona intestinalis cin-let-7a-1-3p mature miRNA
• Sequence: 78 - UGUGUAACCUUCUGCCUUUGU - 98
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 18339653
   Altered miRNA repertoire in the simplified chordate, Oikopleura dioica
   "Fu X, Adamski M, Thompson EM"
   "Mol Biol Evol (2008) 25:1067-1080


2. PubMed ID: 20370911
   miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data
   Hendrix D, Levine M, Shi W
   Genome Biol (2010) 11:R39