Stem-loop aae-mir-8

Accession

MI0013437

Description

Aedes aegypti aae-mir-8 precursor miRNA

Gene family

MIPF0000019; mir-8

Literature search

3 open access papers mention aae-mir-8
(4 sentences)

Sequence

215632 reads, 10753 reads per million, 2 experiments

gucuguucaCAUCUUACCGGGCAGCAUUAGAuauuuuugaaauacuucUAAUACUGUCAGGUAAAGAUGUCguccgaac
....((((((((((((((.(((((.(((((((((((...)))))..)))))).))))).))).))))))).....))))

Structure

gucu    -----       -   G     C      --     u 
    guuc     aCAUCUU ACC GGCAG AUUAGA  uauuu  
    ||||     ||||||| ||| ||||| ||||||  ||||| u
    caag     UGUAGAA UGG CUGUC UAAUcu  auaaa  
----    ccugC       A   A     A      uc     g 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.411: 876043-876121 [+]

Mature aae-miR-8-5p

• Accession: MIMAT0014214
• Description: Aedes aegypti aae-miR-8-5p mature miRNA
• Sequence: 10 - CAUCUUACCGGGCAGCAUUAGA - 31
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-8-3p

• Accession: MIMAT0014215
• Description: Aedes aegypti aae-miR-8-3p mature miRNA
• Sequence: 49 - UAAUACUGUCAGGUAAAGAUGUC - 71
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119