Stem-loop aae-mir-1889

Accession

MI0013448

Description

Aedes aegypti aae-mir-1889 precursor miRNA

Literature search

3 open access papers mention aae-mir-1889
(18 sentences)

Sequence

2728 reads, 140 reads per million, 2 experiments

gaggUAAUCUCAAAUUGUAACAGUGGguugauuuuccuggugaaucccggccuuguccuccgucacaagugugacaagugucucgaaaacguguucgcuauaccCACGUUACAGAUUGGGGUUUCCcc
..((.((((((((.(((((((.((((((.(((....((((......))))....)))....(((((....))))).((((.(.((....)).)..))))..))))))))))))).)))))))).))..

Structure

ga  U        A       A      -------------------------------------------u   uuuc    ug 
  gg AAUCUCAA UUGUAAC GUGGgu                                            gau    cugg  a
  || |||||||| ||||||| ||||||                                            |||    ||||   
  CC UUGGGGUU GACAUUG CACcca                                            cug    ggcc  a
cc  U        A       -      uaucgcuugugcaaaagcucugugaacagugugaacacugccuc   uucc    cu 

Annotation confidence Medium

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.68: 2720794-2720921 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from aae-mir-1889

Mature aae-miR-1889-5p

• Accession: MIMAT0014233
• Description: Aedes aegypti aae-miR-1889-5p mature miRNA
• Sequence: 5 - UAAUCUCAAAUUGUAACAGUGG - 26
• Evidence: experimental ; Illumina [2]

Mature aae-miR-1889-3p

• Accession: MIMAT0014234
• Description: Aedes aegypti aae-miR-1889-3p mature miRNA
• Sequence: 105 - CACGUUACAGAUUGGGGUUUCC - 126
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119