Stem-loop aae-mir-989

Accession

MI0013451

Description

Aedes aegypti aae-mir-989 precursor miRNA

Literature search

8 open access papers mention aae-mir-989
(30 sentences)

Sequence

2327548 reads, 16720.0 reads per million, 81 experiments

uucaucauacggucaugggggacCGCCGCUACCUCGCUUUCACUUGguaccgauuucccauaauccaUGUGAUGUGACGUAGUGGUACcuucccuuggcuauuacaacacuuccu
..........(((((.(((((...((((((((.((((..((((.(((.................))).)))).)))).))))))))...))))).)))))...............

Structure

-----uucaucauac     u     acC        C    UU    U   uaccgau 
               gguca ggggg   GCCGCUAC UCGC  UCAC UGg       u
               ||||| |||||   |||||||| ||||  |||| |||       u
               ucggu cccuu   UGGUGAUG AGUG  AGUG acc       c
uccuucacaacauua     u     cCA        C    -U    U   uaauacc 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

ref|NW_001809968.1|: 804160-804274 [-]

Mature aae-miR-989-5p

• Accession: MIMAT0057323
• Description: Aedes aegypti aae-miR-989-5p mature miRNA
• Sequence: 24 - CGCCGCUACCUCGCUUUCACUUG - 46
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-989-3p

• Accession: MIMAT0014239
• Description: Aedes aegypti aae-miR-989-3p mature miRNA
• Sequence: 68 - UGUGAUGUGACGUAGUGGUAC - 88
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119