Stem-loop aae-mir-1

Accession

MI0013455

Description

Aedes aegypti aae-mir-1 precursor miRNA

Literature search

12 open access papers mention aae-mir-1
(28 sentences)

Sequence

10183851 reads, 36950.0 reads per million, 91 experiments

cgaaaguuCCAUGCUUCCUUGCAUUCAAUAgugauucugaaagcauaUGGAAUGUAAAGAAGUAUGGAGcgcucgg
(((..((((((((((((.((((((((.(((((..........)).))).)))))))).))))))))))))..))).

Structure

-   aa            C        A   -  gauu 
 cga  guuCCAUGCUUC UUGCAUUC AUA gu    c
 |||  |||||||||||| |||||||| ||| ||     
 gcu  cGAGGUAUGAAG AAUGUAAG Uau cg    u
g   cg            A        G   a  aaag 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

ref|NW_001811588.1|: 291326-291401 [+]

Mature aae-miR-1-5p

• Accession: MIMAT0057326
• Description: Aedes aegypti aae-miR-1-5p mature miRNA
• Sequence: 9 - CCAUGCUUCCUUGCAUUCAAUA - 30
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-1-3p

• Accession: MIMAT0014244
• Description: Aedes aegypti aae-miR-1-3p mature miRNA
• Sequence: 48 - UGGAAUGUAAAGAAGUAUGGAG - 69
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119