Stem-loop aae-mir-137-1

Accession

MI0013480

Description

Aedes aegypti aae-mir-137-1 precursor miRNA

Literature search

1 open access papers mention aae-mir-137-1
(2 sentences)

Sequence

819532 reads, 5842.0 reads per million, 81 experiments

uucaucgagcaacuugguuggccACGCGUAUUCUUGGGUUAUUAACacacuguuuauguuguUAUUGCUUGAGAAUACACGUAGuugacaaguguuucacaucg
......(((((.((((.(((((.(((.((((((((((((...(((((.((.......)))))))..)))))))))))).))).)))))))))))))).......

Structure

-uucauc     a    g     c   C            UAU     c  ug 
       gagca cuug uuggc ACG GUAUUCUUGGGU   UAACa ac  u
       ||||| |||| ||||| ||| ||||||||||||   ||||| ||  u
       uuugu gaac aguuG UGC CAUAAGAGUUCG   AUugu ug  u
gcuacac     -    -     A   A            -UU     -  ua 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

ref|NW_001810211.1|: 260664-260767 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from aae-mir-137-1

Mature aae-miR-137-5p

• Accession: MIMAT0057340
• Description: Aedes aegypti aae-miR-137-5p mature miRNA
• Sequence: 24 - ACGCGUAUUCUUGGGUUAUUAAC - 46
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-137-3p

• Accession: MIMAT0014274
• Description: Aedes aegypti aae-miR-137-3p mature miRNA
• Sequence: 63 - UAUUGCUUGAGAAUACACGUAG - 84
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119