Stem-loop aae-mir-133

Accession

MI0013482

Description

Aedes aegypti aae-mir-133 precursor miRNA

Literature search

4 open access papers mention aae-mir-133
(40 sentences)

Sequence

59014 reads, 553.0 reads per million, 80 experiments

cucggaaucgcugaauauAGCUGGUUGACUUCGGGUCAAAUcgucaaauauuugcaaagauauuuccucagugaaaucauUUGGUCCCCUUCAACCAGCUGUagcagugaugcauuaca
......(((((((..(((((((((((((....(((((((((..((((((((((....))))))).......)))....)))))).)))..))))))))))))).)))))))........

Structure

--cucgga       aa             CUUC   -      --cg   -------       g 
        aucgcug  uauAGCUGGUUGA    GGG UCAAAU    uca       aauauuu c
        |||||||  |||||||||||||    ||| ||||||    |||       |||||||  
        uagugac  aUGUCGACCAACU    CCC GGUUua    agu       uuauaga a
acauuacg       -g             --UC   U      cuaa   gacuccu       a 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

ref|NW_001811549.1|: 350289-350407 [-]

Mature aae-miR-133-5p

• Accession: MIMAT0057341
• Description: Aedes aegypti aae-miR-133-5p mature miRNA
• Sequence: 19 - AGCUGGUUGACUUCGGGUCAAAU - 41
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-133-3p

• Accession: MIMAT0014275
• Description: Aedes aegypti aae-miR-133-3p mature miRNA
• Sequence: 81 - UUGGUCCCCUUCAACCAGCUGU - 102
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119