Stem-loop aae-mir-124

Accession

MI0013488

Description

Aedes aegypti aae-mir-124 precursor miRNA

Literature search

7 open access papers mention aae-mir-124
(11 sentences)

Sequence

236836 reads, 639.0 reads per million, 80 experiments

uuuucuccuggUAUCCACUGCCGGCCUAUAUGUccuauuucgguacucaUAAGGCACGCGGUGAAUGCCAAgagcg
....(((.((((((.((((((..((((((..((((......)).))..)).))))..)))))).)))))).)))..

Structure

uuuu   c      C      CG    -  AU  -  ua 
    cuc uggUAU CACUGC  GCCU AU  GU cc  u
    ||| |||||| ||||||  |||| ||  || ||   
    gag ACCGUA GUGGCG  CGGA Ua  ca gg  u
--gc   A      A      CA    A  cu  u  cu 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

ref|NW_001811351.1|: 1664615-1664690 [-]

Mature aae-miR-124-5p

• Accession: MIMAT0057345
• Description: Aedes aegypti aae-miR-124-5p mature miRNA
• Sequence: 12 - UAUCCACUGCCGGCCUAUAUGU - 33
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-124-3p

• Accession: MIMAT0014282
• Description: Aedes aegypti aae-miR-124-3p mature miRNA
• Sequence: 50 - UAAGGCACGCGGUGAAUGCCAA - 71
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119