Stem-loop aae-mir-375

Accession

MI0013504

Description

Aedes aegypti aae-mir-375 precursor miRNA

Literature search

7 open access papers mention aae-mir-375
(9 sentences)

Sequence

123120 reads, 2936.0 reads per million, 84 experiments

uggaagaauccgaguuaCUUAAGCCCAACGUACAGAAACUugaaucugaaugccguucuagauuggcuugcuagaagUUUGUUCGUUUGGCUCGAGUUAugcggauucuucugauc
.(((((((((((.((.((((.((((.((((.(((..((((....((((...((((........))))....))))))))))).)))).)))).)))).)).)))))))))))....

Structure

---u           a  u    A    C    U   GA    ugaa    -aau    uuc 
    ggaagaauccg gu aCUU AGCC AACG ACA  AACU    ucug    gccg   u
    ||||||||||| || |||| |||| |||| |||  ||||    ||||    ||||    
    ucuucuuaggc uA UGAG UCGG UUGC UGU  UUga    agau    cggu   a
cuag           g  U    C    U    U   --    ----    cguu    uag 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

ref|NW_001811029.1|: 1318735-1318850 [-]

Mature aae-miR-375-5p

• Accession: MIMAT0057355
• Description: Aedes aegypti aae-miR-375-5p mature miRNA
• Sequence: 18 - CUUAAGCCCAACGUACAGAAACU - 40
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-375-3p

• Accession: MIMAT0014298
• Description: Aedes aegypti aae-miR-375-3p mature miRNA
• Sequence: 78 - UUUGUUCGUUUGGCUCGAGUUA - 99
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119