Stem-loop hsa-mir-514b

Accession

MI0014251

Symbol

HGNC: MIR514B

Description

Homo sapiens hsa-mir-514b precursor miRNA mir-509

Gene
family

RF04216; mir-509

Literature search

11 open access papers mention hsa-mir-514b
(18 sentences)

Sequence

2137 reads, 114 reads per million, 33 experiments

caugugguacucUUCUCAAGAGGGAGGCAAUCAUguguaauuagauaugAUUGACACCUCUGUGAGUGGAguaacacaug
((((((.((((((.(((((((((....(((((((((........)))))))))...))))).)))).)))))).))))))

Structure

      g      U    -     GAGG         gua 
caugug uacucU CUCA AGAGG    CAAUCAUgu   a
|||||| |||||| |||| |||||    |||||||||    
guacac augAGG GAGU UCUCC    GUUAguaua   u
      a      U    G     -ACA         gau 

Annotation confidence High

Genome context

chrX: 147250151-147250230 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from hsa-mir-514b

Disease association

hsa-mir-514b is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-514b-5p

• Accession: MIMAT0015087
• Description: Homo sapiens hsa-miR-514b-5p mature miRNA
• Sequence: 13 - UUCUCAAGAGGGAGGCAAUCAU - 34
• Evidence: experimental ; Illumina [1-4]

Mature hsa-miR-514b-3p

• Accession: MIMAT0015088
• Description: Homo sapiens hsa-miR-514b-3p mature miRNA
• Sequence: 50 - AUUGACACCUCUGUGAGUGGA - 70
• Evidence: experimental ; Illumina [1,3-4]

References

1. PubMed ID: 20300190
   Characterization of the Melanoma miRNAome by Deep Sequencing
   "Stark MS, Tyagi S, Nancarrow DJ, Boyle GM, Cook AL, Whiteman DC, Parsons PG, Schmidt C, Sturm RA, Hayward NK"
   "PLoS One (2010) 5:e9685


2. PubMed ID: 20224791
   Discovery of novel microRNAs in female reproductive tract using next generation sequencing
   Creighton CJ, Benham AL, Zhu H, Khan MF, Reid JG, Nagaraja AK, Fountain MD, Dziadek O, Han D, Ma L, Kim J, Hawkins SM, Anderson ML, Matzuk MM, Gunaratne PH
   PLoS One (2010) 5:e9637


3. PubMed ID: 20459774
   Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls
   Witten D, Tibshirani R, Gu SG, Fire A, Lui WO
   BMC Biol (2010) 8:58


4. PubMed ID: 21199797
   Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene
   "Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C"
   "Cancer Res (2011) 71:78-86