Stem-loop hsa-mir-4524a

Accession

MI0016891

Symbol

HGNC: MIR4524A

Description

Homo sapiens hsa-mir-4524a precursor miRNA mir-4524

Gene
family

RF03781; mir-4524

Literature search

1 open access papers mention hsa-mir-4524a
(1 sentences)

Sequence

498 reads, 4 reads per million, 41 experiments

gaacgAUAGCAGCAUGAACCUGUCUCAcugcagaauuauuuUGAGACAGGCUUAUGCUGCUAUccuuca
(((.(((((((((((((.(((((((((..............))))))))).))))))))))))).))).

Structure

-   c             A         cugcag 
 gaa gAUAGCAGCAUGA CCUGUCUCA      a
 ||| ||||||||||||| |||||||||       
 cuu cUAUCGUCGUAUU GGACAGAGU      a
a   c             C         uuuauu 

Annotation confidence High

Genome context

chr17: 69099564-69099632 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-4524a

Disease association

hsa-mir-4524a is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-4524a-5p

• Accession: MIMAT0019062
• Description: Homo sapiens hsa-miR-4524a-5p mature miRNA
• Sequence: 6 - AUAGCAGCAUGAACCUGUCUCA - 27
• Evidence: experimental ; Illumina [1-2,4]

Mature hsa-miR-4524a-3p

• Accession: MIMAT0019063
• Description: Homo sapiens hsa-miR-4524a-3p mature miRNA
• Sequence: 42 - UGAGACAGGCUUAUGCUGCUAU - 63
• Evidence: experimental ; Illumina [1-2,4]

References

1. PubMed ID: 20733160
   Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs
   "Jima DD, Zhang J, Jacobs C, Richards KL, Dunphy CH, Choi WW, Au WY, Srivastava G, Czader MB, Rizzieri DA, Lagoo AS, Lugar PL, Mann KP, Flowers CR, Bernal-Mizrachi L, Naresh KN, Evens AM, Gordon LI, Luftig M, Friedman DR, Weinberg JB, Thompson MA, Gill JI,"
   "Blood (2010) 116:e118-e127


2. PubMed ID: 21199797
   Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene
   "Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C"
   "Cancer Res (2011) 71:78-86


3. PubMed ID: 21911355
   miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
   "Friedlander MR, Mackowiak SD, Li N, Chen W, Rajewsky N"
   "Nucleic Acids Res (2012) 40:37-52


4. PubMed ID: 21807764
   Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome
   "Joyce CE, Zhou X, Xia J, Ryan C, Thrash B, Menter A, Zhang W, Bowcock AM"
   "Hum Mol Genet (2011) 20:4025-4040