miRBase entry: aae-mir-34

Stem-loop aae-mir-34


Accession
MI0013456
Description
Aedes aegypti aae-mir-34 precursor miRNA
Gene family
MIPF0000039; mir-34

Literature search
5 open access papers mention aae-mir-34
(26 sentences)

Sequence

922392 reads, 45559 reads per million, 2 experiments
caaggcaauacgcuaUGGCAGUGUGGUUAGCUGGUUGuguagaacuuuggggggcuuccguggcguucgcgcgcacacgggggcucagauucaCAACCACUAUCCGCCCUGCCGCCgcgaggugccagg
...((((...(((..((((((.((((.(((.((((((((............(((((((((((((((....)))).))))))))))).....))))))))))).)))).))))))..)))...))))...

Structure
caa    aua   ua      U    U   C        uagaacuuuggg           -    u 
   ggca   cgc  UGGCAG GUGG UAG UGGUUGug            gggcuuccgug gcgu c
   ||||   |||  |||||| |||| ||| ||||||||            ||||||||||| ||||  
   ccgu   gcg  GCCGUC CGCC AUC ACCAACac            cucgggggcac cgcg g
gga    gga   CC      C    U   -        -------uuaga           a    c 


Annotation confidence High
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Comments
This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context
supercont1.265: 509521-509649 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from aae-mir-34
Name Accession Chromosome Start End Strand Confidence




Database links

Mature aae-miR-34-5p

Accession MIMAT0014245
Description Aedes aegypti aae-miR-34-5p mature miRNA
Sequence 16 - UGGCAGUGUGGUUAGCUGGUUG - 37
Evidence experimental
454 [1], Illumina [2]

Mature aae-miR-34-3p

Accession MIMAT0014246
Description Aedes aegypti aae-miR-34-3p mature miRNA
Sequence 94 - CAACCACUAUCCGCCCUGCCGCC - 116
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 19961592
    Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
    Li S, Mead EA, Liang S, Tu Z
    BMC Genomics (2009) 10:581

  2. PubMed ID: 20167119
    Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
    Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
    BMC Genomics (2010) 11:119