miRBase entry: dme-mir-8

Stem-loop dme-mir-8


Accession
MI0000128
Description
Drosophila melanogaster dme-mir-8 precursor miRNA mir-8
Gene
family?
RF00241; mir-8

Literature search
38 open access papers mention dme-mir-8
(296 sentences)

Sequence

9125445 reads, 57465 reads per million, 49 experiments
aaggacaucuguucaCAUCUUACCGGGCAGCAUUAGAuccuuuuuauaacucUAAUACUGUCAGGUAAAGAUGUCguccguguccuu
((((((((......((((((((((.(((((.((((((.............)))))).))))).))).))))))).....))))))))

Structure
        cuguuc       -   G     C      uccuu 
aaggacau      aCAUCUU ACC GGCAG AUUAGA     u
||||||||      ||||||| ||| ||||| ||||||     u
uuccugug      UGUAGAA UGG CUGUC UAAUcu     u
        -ccugC       A   A     A      caaua 


Annotation confidence High
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Genome context
chr2R: 16831432-16831518 [+]

Database links

Mature dme-miR-8-3p

Accession MIMAT0000113
Description Drosophila melanogaster dme-miR-8-3p mature miRNA
Sequence 53 - UAAUACUGUCAGGUAAAGAUGUC - 75
Evidence experimental
cloned [1,3], Northern [1-3], 454 [4-5], Illumina [5]
Database links
Predicted targets

Mature dme-miR-8-5p

Accession MIMAT0020791
Description Drosophila melanogaster dme-miR-8-5p mature miRNA
Sequence 16 - CAUCUUACCGGGCAGCAUUAGA - 37
Evidence not_experimental
Database links

References

  1. PubMed ID: 11679670
    Identification of novel genes coding for small expressed RNAs
    "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
    "Science (2001) 294:853-858

  2. PubMed ID: 12812784
    Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    "Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V"
    "Dev Biol (2003) 259:9-18

  3. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  4. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  5. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879